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RIAM/APBB1IP Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: RIAM/APBB1IP Antibody [NBP2-39009] - Analysis in human lymph node and heart muscle tissues. Corresponding RIAM/APBB1IP RNA-seq data are presented for the same ...read more
Independent Antibodies: Immunohistochemistry-Paraffin: RIAM/APBB1IP Antibody [NBP2-39009] - Staining of human cerebral cortex, colon, heart muscle and lymph node using Anti-RIAM/APBB1IP antibody NBP2-39009 (A) ...read more
Immunocytochemistry/ Immunofluorescence: RIAM/APBB1IP Antibody [NBP2-39009] - Immunofluorescent staining of human cell line BJ shows localization to plasma membrane & cytosol.
Immunohistochemistry-Paraffin: RIAM/APBB1IP Antibody [NBP2-39009] - Staining of human lymph node shows very strong cytoplasmic positivity in germinal center cells.
Immunohistochemistry-Paraffin: RIAM/APBB1IP Antibody [NBP2-39009] - Staining of human cerebral cortex shows strong cytoplasmic positivity in glial cells.
Immunohistochemistry-Paraffin: RIAM/APBB1IP Antibody [NBP2-39009] - Staining of human colon shows strong cytoplasmic positivity in lymphoid cells.
Immunohistochemistry-Paraffin: RIAM/APBB1IP Antibody [NBP2-39009] - Staining of human heart muscle shows no positivity in cardiomyocytes as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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RIAM/APBB1IP Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: KTLYDNYQRAVAKAGLASRWTNLGTVNAAAPAQPSTGPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSKDKKPAL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
APBB1IP
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
RIAM/APBB1IP Protein (NBP2-39009PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for RIAM/APBB1IP Antibody

  • amyloid beta (A4) precursor protein-binding, family B, member 1 interactingprotein
  • amyloid beta A4 precursor protein-binding family B member 1-interacting protein
  • APBB1-interacting protein 1
  • APBB1IP
  • INAG1
  • PREL1
  • PREL-1
  • proline rich EVH1 ligand 1
  • Proline-rich EVH1 ligand 1
  • Proline-rich protein 73
  • Rap1-GTP-interacting adapter molecule
  • Rap1-interacting adaptor molecule
  • RARP1
  • Retinoic acid-responsive proline-rich protein 1
  • RIAM
  • RIAMRARP-1

Background

Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

ICC/IF Video Protocol

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Bioinformatics

Gene Symbol APBB1IP
Uniprot