RGM-C/Hemojuvelin Antibody (DISC-0974) - Humanized Summary
Description |
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles. |
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
RGMC / HFE2 |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Human |
Gene |
HJV, HFE2 |
Purity |
Protein A purified |
Endotoxin Note |
< 0.001EU/ug,determined by LAL method. |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA
- Flow Cytometry
- Functional
|
Packaging, Storage & Formulations
Storage |
Store at -20C in powder form. Store at -80C once reconstituted. |
Buffer |
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2) |
Preservative |
No Preservative |
Concentration |
LYOPH |
Purity |
Protein A purified |
Reconstitution Instructions |
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex. |
Alternate Names for RGM-C/Hemojuvelin Antibody (DISC-0974) - Humanized
Background
The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu
Applications: ELISA
Species: Hu
Applications: IHC, IHC-P, WB
Species: Ch
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: ELISA, ICC/IF, WB
Species: Hu
Applications: Simple Western, WB
Species: Hu
Applications: BA
Species: Ca, Hu, Mu, Rt
Applications: IHC, IHC-P, IP, WB
Species: Hu, Mu, Rt
Applications: BA
Species: Hu
Applications: BA
Species: Hu
Applications: IHC, IHC-P, WB
Species: Mu
Applications: ELISA
Species: Bv, Hu, Mu, Po, Rt
Applications: Flow-IC, Flow, ICC/IF, IHC, IHC-P, WB
Species: Hu, Mu
Applications: Block, IHC, Simple Western, WB
Species: Hu
Applications: BA, BA
Species: Hu
Applications: BA
Species: Hu, Mu
Applications: Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
Species: Hu
Applications: CyTOF-ready, ELISA, Flow, ICC/IF, IHC, IHC-P, PA, WB
Species: Mu
Applications: Bind
Publications for RGM-C/Hemojuvelin Antibody (NBP3-28395) (0)
There are no publications for RGM-C/Hemojuvelin Antibody (NBP3-28395).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for RGM-C/Hemojuvelin Antibody (NBP3-28395) (0)
There are no reviews for RGM-C/Hemojuvelin Antibody (NBP3-28395).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for RGM-C/Hemojuvelin Antibody (NBP3-28395) (0)
Secondary Antibodies
| |
Isotype Controls
|
Additional RGM-C/Hemojuvelin Products
Blogs on RGM-C/Hemojuvelin