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REXO2 Antibody

Images

 
Western Blot: REXO2 Antibody [NBP1-85666] - Analysis in human cell line U-2 OS.
Immunocytochemistry/ Immunofluorescence: REXO2 Antibody [NBP1-85666] - Staining of human cell line U-251 MG shows positivity in mitochondria. Antibody staining is shown in green.
Orthogonal Strategies: Immunohistochemistry-Paraffin: REXO2 Antibody [NBP1-85666] - Staining in human parathyroid gland and skeletal muscle tissues using anti-REXO2 antibody. Corresponding REXO2 RNA-seq data are ...read more
Immunohistochemistry-Paraffin: REXO2 Antibody [NBP1-85666] - Staining of human parathyroid gland shows high expression.
Immunohistochemistry-Paraffin: REXO2 Antibody [NBP1-85666] - Staining of human skeletal muscle shows low expression as expected.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

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REXO2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: YRIIDVSTVKELCRRWYPEEYEFAPKKAASHRALDDISESIKELQFYRNNIFKKKIDEKKRKIIENGENEKTVS
Predicted Species
Mouse (95%), Rat (96%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
REXO2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
REXO2 Protein (NBP1-85666PEP)
Publications
Read Publication using NBP1-85666.

Reactivity Notes

Reactivity reported in scientific literature (PMID: 23435261)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for REXO2 Antibody

  • CGI-114
  • DKFZp566E144
  • EC 3.1
  • oligoribonuclease, mitochondrial
  • REX2
  • REX2, RNA exonuclease 2 homolog (S. cerevisiae)
  • RFN
  • RNA exonuclease 2 homolog
  • SFNMGC111570
  • Small fragment nuclease
  • SMFN

Background

REXO2, also known as Oligoribonuclease, mitochondrial, is a 27kDa 237 amino acid protein with a shorter 23kDa 199 isoform. This gene plays a significant role in reparing DNA and is believed to play a role in aiding cells resist UV-C-induced death. REXO2 has been studied in relation to t-cell leukemia, leukemia, tuberculosis and mycobacterium tuberculosis. REXO2 is linked to the ribosome biogenesis in eukaryotes pathway where it interacts with ATG5, MPG, DIS3, UBC and EXOSC10.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for REXO2 Antibody (NBP1-85666)(1)

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for REXO2 Antibody (NBP1-85666) (0)

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Secondary Antibodies

 

Isotype Controls

Additional REXO2 Products

Research Areas for REXO2 Antibody (NBP1-85666)

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Blogs on REXO2

There are no specific blogs for REXO2, but you can read our latest blog posts.
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Bioinformatics

Gene Symbol REXO2