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REXO1 Antibody [Alexa Fluor® 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Alexa Fluor 488

Order Details

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REXO1 Antibody [Alexa Fluor® 488] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human REXO1 fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
REXO1
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for REXO1 Antibody [Alexa Fluor® 488]

  • EC 3.1
  • ELOABP1elongin A-binding protein 1
  • EloA-BP1REX1
  • Elongin-A-binding protein 1
  • KIAA1138elongin A binding protein 1
  • REX1, RNA exonuclease 1 homolog (S. cerevisiae)
  • TCEB3BP1RNA exonuclease 1 homolog
  • transcription elongation factor B polypeptide 3 binding protein 1
  • Transcription elongation factor B polypeptide 3-binding protein 1

Background

REXO1 or Elongin A-binding protein 1 (EloA-BP1) is an exonuclease domain-containing protein that can bind to Elongin. The Elongin complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. REXO1 is composed of 1221 amino acids and its mRNA is ubiquitously expressed. EloA-BP1 is capable of binding not only the NH(2)-terminal approximately 120 amino acid region of Elongin A, but also that of SII. Although REXO1 had no detectable effect on the rate of transcription elongation in vitro, it may play some role in the regulation of elongation in vivo.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional REXO1 Products

Array NBP2-98052AF488

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Bioinformatics

Gene Symbol REXO1