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RCOR1/CoREST Antibody [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 585

Order Details

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RCOR1/CoREST Antibody [Janelia Fluor® 585] Summary

Immunogen
A synthetic peptide that maps to a region between residues 425 and the C-terminus (residue 482) of human REST (RE1-silencing transcription factor) corepressor using the numbering given in entry NP_055971.1 (GeneID 23186)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RCOR1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for RCOR1/CoREST Antibody [Janelia Fluor® 585]

  • CoREST
  • KIAA0071CORESTRCORREST corepressor
  • Protein CoREST
  • RCOR1
  • RCOR1/CoREST
  • REST corepressor 1

Background

Brain type II sodium channels are important in neuronal phenotyping and are only seen at high levels in neurons. Studies have shown that CoREST functions as a corepressor for REST. This interaction between REST and CoREST is accomplished by means of a single zinc finger binding motif originating from REST. Together, the REST-CoREST complex mediates long term repression of the type II sodium channel gene (1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol RCOR1