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RCE1 Antibody

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Immunohistochemistry-Paraffin: RCE1 Antibody [NBP3-17425] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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RCE1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LTDPKLYGSLPLCVLLERAGDSEAPLCS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RCE1
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for RCE1 Antibody

  • CAAX prenyl protease 2
  • EC 3.4.22.-
  • FACE-2
  • FACE2RCE1 homolog, prenyl protein protease (S. cerevisiae)
  • farnesylated protein-converting enzyme 2
  • Farnesylated proteins-converting enzyme 2
  • hRCE1
  • Prenyl protein-specific endoprotease 2
  • RCE1 (S. Cerevisiae) homolog, prenyl protein protease
  • RCE1 homolog
  • RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
  • RCE1 homolog, prenyl protein protease
  • RCE1A
  • RCE1B

Background

RCE1, also known as CAAX prenyl protease 2, is a 36 kDa 329 amino acid protein found in the endoplasmic reticulum membrane. The primary function of RCE1 is to encode a protein that plays a signifcant role in the processing and maintenance of CAAX-type proteins. Research is being conducted on RCE1 in relation tofollicular mucinosis, mandibuloacral dysplasia, phaeohyphomycosis, Legionnaires' disease, impetigo, cardiomyopathy. RCE1 is linked to the G-protein signaling Rap1A regulation pathway where it interacts with ICMT, UBC, EIF3F and ZMPSTE24.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol RCE1