RAX Antibody Summary
Immunogen |
A portion of amino acids 300-350 of human Rax was used as the immunogen. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
RAX |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Reactivity Notes
Reacts with New World Monkey. 85% sequence identity with chicken and 78% with zebrafish, mouse and rat proteins.
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS containing 0.2% gelatin |
Preservative |
0.05% Sodium Azide |
Concentration |
0.5 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for RAX Antibody
Background
Principal Names: Retinal and anterior neural fold Homeobox (Rax); Retinal Homeobox protein Rx; Official Gene Symbol: RAX Gen Bank Accession Number: NP_038463 Gene ID: 30062 (Human) Gene Map Locus: 18q21.32 (Human) Rax, a novel transcription factor, is a human homolog of Drosophila Rx protein. It is a significant member of Rx protein family and consists of a highly-conserved N-terminal DNA-binding paired-like Homeodomain. It interacts with PCE-1 and is one of the earliest expressed proteins stimulating establishment and proliferation of retinal progenitor cells. Its expression is essential in determining the fate of normal eye development. Irregular expression of Rax has profound effects on eye morphogenesis. Mutations in Rax gene have been detected in clinical conditions like Anophthalmia and Sclerocornea.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for RAX Antibody (NB100-56467) (0)
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Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
Video Protocols
FAQs for RAX Antibody (NB100-56467). (Showing 1 - 1 of 1 FAQ).
-
Does this product work in zebrafish?
- NB100-56467 has been validated in human, canine, and primate. We have not yet tested this in zebrafish. The immunogen used (from human RAX) shares a 78% homology with zebrafish, so there may be some potential for cross reaction. However, we do not have any testing information nor can we guarantee performance in zebrafish.
Control Lysate(s)
Secondary Antibodies
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Isotype Controls
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