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PRPF8 Antibody [DyLight 350]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 350

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PRPF8 Antibody [DyLight 350] Summary

Immunogen
The immunogen this antibody was made to, maps to a region between residue 2285 and 2335 of human Pre-mRNA-Processing Factor 8 using the numbering given in entry NP_006436.3 (GeneID 10594).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PRPF8
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PRPF8 Antibody [DyLight 350]

  • apoptosis-regulated protein 1
  • apoptosis-regulated protein 2
  • p220
  • precursor mRNA processing protein
  • pre-mRNA-processing-splicing factor 8
  • PRP8 homolog
  • PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)
  • PRP8 pre-mRNA processing factor 8 homolog (yeast)
  • Prp8
  • PRP8,220 kDa U5 snRNP-specific protein
  • PRPC8HPRP8
  • RP13
  • Splicing factor Prp8
  • U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p

Background

Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Array NBP2-22274UV

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Bioinformatics

Gene Symbol PRPF8