PRPF8 Products

Description

Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq]

Bioinformatics

Entrez	10594 Human
Uniprot	Q6P2Q9 Human
Product By Gene ID	10594
Alternate Names	apoptosis-regulated protein 1 apoptosis-regulated protein 2 p220 precursor mRNA processing protein pre-mRNA-processing-splicing factor 8 PRP8 homolog PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) PRP8 pre-mRNA processing factor 8 homolog (yeast) Prp8 PRP8,220 kDa U5 snRNP-specific protein PRPC8HPRP8 RP13 Splicing factor Prp8 U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p

Research Areas for PRPF8

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