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Prostaglandin E Synthase Recombinant Protein Antigen

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Summary
Reactivity HuSpecies Glossary
Applications AC

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Prostaglandin E Synthase Recombinant Protein Antigen Summary

Description
A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human PTGES.

Source: E. coli

Amino Acid Sequence: ITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAPRNDM

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.
Source
E. coli
Protein/Peptide Type
Recombinant Protein Antigen
Gene
PTGES
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Dilutions
  • Antibody Competition 10 - 100 molar excess
Application Notes
This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP1-87852.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Theoretical MW
23 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 1M Urea, pH 7.4.
Preservative
No Preservative
Purity
>80% by SDS-PAGE and Coomassie blue staining

Alternate Names for Prostaglandin E Synthase Recombinant Protein Antigen

  • EC 5.3.99.3
  • MGC10317
  • MGST1L1
  • MGST1-L1
  • MGST1L1MGST1-like 1
  • MGST1-L1mPGES-1
  • MGST-IV
  • Microsomal glutathione S-transferase 1-like 1
  • Microsomal prostaglandin E synthase 1
  • MPGES
  • MPGES1
  • MPGES-1
  • p53-induced apoptosis protein 12
  • p53-induced gene 12 protein
  • PGES
  • PGESmicrosomal prostaglandin E synthase-1
  • PIG12
  • PIG12glutathione S-transferase 1-like 1
  • PP102
  • PP1294
  • Prostaglandin E Synthase
  • PTGES
  • TP53I12
  • tumor protein p53 inducible protein 12

Background

Prostaglandin E Synthase is encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Prostaglandin E
Synthase Recombinant ...
NBP1-87852PEP
Prostaglandin E Synthase Recombinant Protein Antigen
Species: Hu
Applications: AC

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Bioinformatics

Gene Symbol PTGES