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Proprotein Convertase 9/PCSK9 Antibody (Hu135) [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications CyTOF-ready, Flow
Clone
Hu135
Clonality
Monoclonal
Host
Human
Conjugate
DyLight 594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC10347U-100UG
Alexa Fluor 405
IC10347V-100UG
Alexa Fluor 488
IC10347G-100UG
Alexa Fluor 532
FAB10347X
Alexa Fluor 594
IC10347T-100UG
Alexa Fluor 647
IC10347R-100UG
Alexa Fluor 700
IC10347N-100UG
Alexa Fluor 750
IC10347S-100UG
Allophycocyanin
FAB10347A
Biotin
FAB10347B
CoraFluor 1
FAB10347CL1
DyLight 350
FAB10347D
DyLight 405
FAB10347E
DyLight 488
FAB10347K
DyLight 550
FAB10347L
DyLight 650
FAB10347W
DyLight 680
FAB10347Y
DyLight 755
FAB10347Z
FITC
FAB10347F
HRP
FAB10347H
Janelia Fluor 525
FAB10347JF525
Janelia Fluor 549
FAB10347I
Janelia Fluor 646
FAB10347J
Janelia Fluor 669
FAB10347JF669
PE
FAB10347P
PerCP
FAB10347C
Unconjugated
MAB10347-100
mFluor Violet 450 SE
FAB10347MFV450
mFluor Violet 500 SE
FAB10347MFV500
mFluor Violet 610 SE
FAB10347MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB10347-100
Carrier Free
MAB10347-100
Carrier Free
MAB10347-SP
Carrier Free
IC10347G-100UG
Carrier Free
IC10347V-100UG
Carrier Free
IC10347U-100UG
Carrier Free
IC10347T-100UG
Carrier Free
IC10347S-100UG
Carrier Free
IC10347R-100UG
Carrier Free
IC10347N-100UG
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Proprotein Convertase 9/PCSK9 Antibody (Hu135) [DyLight 594] Summary

Immunogen
Human Proprotein Convertase 9/PCSK9
Specificity
Detccts Human Proprotein Convertase 9/PCSK9 in direct ELISAs. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Alirocumab. This product is for research use only.
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Purity
Protein A or G purified from cell culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from cell culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Proprotein Convertase 9/PCSK9 Antibody (Hu135) [DyLight 594]

  • EC 3.4.21
  • EC 3.4.21.111
  • FH3
  • FH3neural apoptosis regulated convertase 1
  • FHCL3
  • HCHOLA3
  • hypercholesterolemia, autosomal dominant 3
  • LDLCQ1
  • NARC1
  • NARC-1
  • NARC-1convertase subtilisin/kexin type 9 preproprotein
  • NARC1EC 3.4.21.-
  • Neural apoptosis-regulated convertase 1
  • PC9
  • PCSK9
  • Proprotein Convertase 9
  • proprotein convertase subtilisin/kexin type 9
  • Subtilisin/kexin-like protease PC9

Background

PCSK9 encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Proprotein
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FAB10347M
Proprotein Convertase 9/PCSK9 Antibody (Hu135) [DyLight 594]
Species: Hu
Applications: CyTOF-ready, Flow

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