Proprotein Convertase 9/PCSK9 Antibody (Hu135) [Janelia Fluor® 525] Summary
Additional Information |
Recombinant Monoclonal Antibody For Research Use Only |
Immunogen |
Human Proprotein Convertase 9/PCSK9 |
Specificity |
Detccts Human Proprotein Convertase 9/PCSK9 in direct ELISAs. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Alirocumab. This product is for research use only. |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Human |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- CyTOF-ready
- Intracellular Staining by Flow Cytometry
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Notes
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
Alternate Names for Proprotein Convertase 9/PCSK9 Antibody (Hu135) [Janelia Fluor® 525]
Background
PCSK9 encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for Proprotein Convertase 9/PCSK9 Antibody (FAB10347JF525) (0)
Secondary Antibodies
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