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Profilin 2 Antibody (010) [PerCP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
010
Clonality
Monoclonal
Host
Rabbit
Conjugate
PerCP

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Profilin 2 Antibody (010) [PerCP] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Human Profilin 2 (Accession#: AAH18049.1; Met1-Phe140).
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
PFN2
Purity
Protein A purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for Profilin 2 Antibody (010) [PerCP]

  • D3S1319E
  • PFL
  • profilin 2
  • Profilin II
  • profilin-2

Background

Profilin 2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals by binding to actin (1:1 ratio) and so affecting the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Highly expressed in skeletal muscle, kidney and brain and less strongly in placenta, heart, liver and lung.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Profilin 2 Antibody (NBP2-90284PCP) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Profilin 2 Antibody (NBP2-90284PCP) (0)

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Secondary Antibodies

 

Isotype Controls

Additional Profilin 2 Products

Research Areas for Profilin 2 Antibody (NBP2-90284PCP)

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Blogs on Profilin 2.

Profiling the Profilin 1 Antibody
Profilin-1, or Pfn-1, is a small actin-binding protein which plays an essential role controlling the growth of microfilaments. Profilin 1 and Profilin 2 have similar biochemical properties but are expressed in different tissues. The Profilin 1 antibod...  Read full blog post.

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Bioinformatics

Gene Symbol PFN2