Profilin 2 Products

Description

Profilin 2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals by binding to actin (1:1 ratio) and so affecting the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Highly expressed in skeletal muscle, kidney and brain and less strongly in placenta, heart, liver and lung.

Bioinformatics

Entrez	18643 Mouse 5217 Human 64303 Rat
Uniprot	AAH18049 Human AAH18049.1 Human NM_002628 Human NM_053024 Human NP_002619 Human
Product By Gene ID	5217
Alternate Names	D3S1319E PFL profilin 2 Profilin II profilin-2

Research Areas for Profilin 2

Find related products by research area and learn more about each of the different research areas below.

Cytoskeleton Markers
Loading Controls
Signal Transduction
Stem Cell Markers

Related Profilin 2 Blog Posts

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Profiling the Profilin 1 Antibody Profilin-1, or Pfn-1, is a small actin-binding protein which plays an essential role controlling the growth of microfilaments. Profilin 1 and Profilin 2 have similar biochemical properties but are expressed in different tissues. The Profilin 1 antibod...    Read more.

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