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preproANP Antibody

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Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-34105] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-34105] - Staining of human heart muscle shows high expression.
Orthogonal Strategies: Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-34105] - Staining in human heart muscle and skeletal muscle tissues using anti-preproANP antibody. Corresponding preproANP RNA-seq ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

preproANP Antibody Summary

Immunogen
This antibody was developed against recombinant preproANP protein corresponding to amino acids: GQTRANPMYNAVSNADLMDFKNLLDHLEEKMPLEDEVVPPQVLSEPNEEAGAALSPLPEVPPWT
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NPPA
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:5000 - 1:10000
  • Immunohistochemistry-Paraffin 1:5000 - 1:10000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
preproANP Recombinant Protein Antigen (NBP2-34105PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (81%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for preproANP Antibody

  • ANF
  • ANP
  • ATFB6
  • atrial natriuretic factor prohormone
  • atrial natriuretic peptide prohormone
  • ATRST2
  • CDD
  • CDD-ANF
  • CDP
  • natriuretic peptides A
  • PND

Background

The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NPPA
Uniprot