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Polycystin 2 Antibody

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Western Blot: Polycystin 2 Antibody [NBP1-51975] - (1ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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Polycystin 2 Antibody Summary

Immunogen
Peptide with sequence C-ERAKLKRREVLGR corresponding to internal region according to NP_000288.1.
Epitope
C-ERAKLKRREVLGR
Predicted Species
Mouse (100%), Rat (100%), Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
PKD2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:2000
  • Western Blot 1 - 3 ug/ml
Application Notes
WB: Approx. 100 kDa band observed in HeLa lysate (calculated MW of 110 kDa band according to NP_000288.1).
Publications
Read Publication using NBP1-51975.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Polycystin 2 Antibody

  • APKD2
  • Autosomal dominant polycystic kidney disease type II protein
  • MGC138466
  • MGC138468
  • PC2
  • Pc-2
  • PKD4
  • polycystic kidney disease 2 (autosomal dominant)
  • Polycystic kidney disease 2 protein
  • polycystin-2
  • polycystwin
  • R48321
  • transient receptor potential cation channel, subfamily P, member 2
  • TRPP2

Background

FUNCTION: Functions as a calcium permeable cation channel. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. SUBUNIT: Interacts with PKD1. PKD1 requires the presence of PKD2 for stable expression. Interacts with CD2AP. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in mesenchymally derived structures in the developing embryo at day 12.5. In adult, mostly expressed in kidney.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Polycystin 2 Antibody (NBP1-51975)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PKD2
Entrez
Uniprot