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PDE11A Antibody

Images

 
Western Blot: PDE11A Antibody [NBP2-19743] - Sample (30 ug of whole cell lysate) A: PC-3 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: PDE11A Antibody [NBP2-19743] - Immunohistochemical analysis of paraffin-embedded U87 xenograft, using antibody at 1:500 dilution.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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PDE11A Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human PDE11A. The exact sequence is proprietary.
Localization
Cytoplasm; cytosol
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PDE11A
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
105 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 20% Glycerol, 1% BSA
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for PDE11A Antibody

  • cAMP and cGMP cyclic nucleotide phosphodiesterase 11A
  • cAMP and cGMP phosphodiesterase 11A
  • cyclic nucleotide phosphodiesterase 11A
  • dual 3'-5'-cyclic-AMP and -GMP phosphodiesterase 11A
  • EC 3.1.4
  • EC 3.1.4.17
  • EC 3.1.4.35
  • EC 3.1.4.53
  • FLJ23693
  • MGC133355
  • MGC133356
  • PDE11A
  • PDE11A1
  • PDE11A2
  • PDE11A3
  • phosphodiesterase 11A
  • PPNAD2

Background

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PDE11A
Uniprot