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PDE11A Antibody

Images

 
Western Blot: PDE11A Antibody [NBP1-85919] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells) Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)
Immunohistochemistry-Paraffin: PDE11A Antibody [NBP1-85919] - Staining of human prostate shows moderate cytoplasmic and membranous positivity in glandular cells.
Western Blot: PDE11A Antibody [NBP1-85919] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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PDE11A Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: VVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVA
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PDE11A
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
PDE11A Protein (NBP1-85919PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for PDE11A Antibody

  • cAMP and cGMP cyclic nucleotide phosphodiesterase 11A
  • cAMP and cGMP phosphodiesterase 11A
  • cyclic nucleotide phosphodiesterase 11A
  • dual 3'-5'-cyclic-AMP and -GMP phosphodiesterase 11A
  • EC 3.1.4
  • EC 3.1.4.17
  • EC 3.1.4.35
  • EC 3.1.4.53
  • FLJ23693
  • MGC133355
  • MGC133356
  • PDE11A
  • PDE11A1
  • PDE11A2
  • PDE11A3
  • phosphodiesterase 11A
  • PPNAD2

Background

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PDE11A