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Pappalysin-1/PAPP-A Antibody (PAPP A 1-1) [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC
Clone
PAPP A 1-1
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 610 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-21614AF350
Alexa Fluor 405
NBP2-21614AF405
Alexa Fluor 488
NBP2-21614AF488
Alexa Fluor 532
NBP2-21614AF532
Alexa Fluor 594
NBP2-21614AF594
Alexa Fluor 647
NBP2-21614AF647
Alexa Fluor 700
NBP2-21614AF700
Alexa Fluor 750
NBP2-21614AF750
Biotin
NBP2-21614B
CoraFluor 1
NBP2-21614CL1
DyLight 350
NBP2-21614UV
DyLight 405
NBP2-21614V
DyLight 488
NBP2-21614G
DyLight 550
NBP2-21614R
DyLight 594
NBP2-21614DL594
DyLight 650
NBP2-21614C
DyLight 680
NBP2-21614FR
DyLight 755
NBP2-21614IR
FITC
NBP2-21614F
HRP
NBP2-21614H
Janelia Fluor 525
NBP2-21614JF525
Janelia Fluor 549
NBP2-21614JF549
Janelia Fluor 646
NBP2-21614JF646
Janelia Fluor 669
NBP2-21614JF669
Unconjugated
NBP2-21614
mFluor Violet 450 SE
NBP2-21614MFV450
mFluor Violet 500 SE
NBP2-21614MFV500
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-21614
BSA Free
NBP2-21614
BSA Free
NBP2-21614-0.025ml
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Pappalysin-1/PAPP-A Antibody (PAPP A 1-1) [mFluor Violet 610 SE] Summary

Immunogen
Purified human PAPP-A
Epitope
The epitope is located on the PAPP-A subunit of the heterotetramer.
Specificity
Specific for native human PAPP-A.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PAPPA
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Pappalysin-1/PAPP-A Antibody (PAPP A 1-1) [mFluor Violet 610 SE]

  • ASBABP2
  • DIPLA1
  • EC 3.4.24.79
  • IGFBP-4ase
  • IGFBP-4aseaspecific BCL2 ARE-binding protein 2
  • IGF-dependent IGFBP-4 protease
  • insulin-like growth factor-dependent IGF binding protein-4 protease
  • Insulin-like growth factor-dependent IGF-binding protein 4 protease
  • PAPA
  • PAPPA
  • PAPPA1
  • PAPP-A1
  • PAPP-Adifferentially placenta 1 expressed protein
  • Pappalysin1
  • Pappalysin-1
  • pregnacy-associated plasma protein A
  • Pregnancy-associated plasma protein A
  • pregnancy-associated plasma protein A, pappalysin 1

Background

PAPP A was originally isolated from pregnancy serum as heterotetrameric protein complex with molecular weight approximately 500 kDa, consisting of two PAPP A subunits disulfide-linked with two subunits of the proform of eosinophil major basic protein (proMBP). In such a complex proMBP functions as an inhibitor of PAPP A proteinase activity. PAPP A is widely used as a marker of some pathologies during pregnancy. Reduced level of PAPP A in pregnancy blood in the first trimester is associated with fetal Down syndrome. PAPP A is considered as one of the best biochemical markers in early pregnancy used to screen for Down syndrome during the first trimester (Wald, N. J. et al).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Pappalysin-1/PAPP-A An ...
NBP2-21614MFV610
Pappalysin-1/PAPP-A Antibody (PAPP A 1-1) [mFluor Violet 610 SE]
Species: Hu
Applications: WB, ELISA, IHC

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FAQs for Pappalysin-1/PAPP-A Antibody (NBP2-21614MFV610). (Showing 1 - 1 of 1 FAQ).

  1. I am highly interested to use couple of Anti-PAPP-A antibodies from your reputed companies for my research work. I have got the information regarding the immunogen used to generate these antibodies, however could not get any information regarding the specific amino acids/epitope to which your Anti-PAPP-A Antibodies binds with the antigen (PAPP-A).
    • Unfortunately, none of our PAPP A antibodies have been epitope mapped. Many of them have also been generated against full-length PAPP A, so there are many potential binding sites.

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Bioinformatics

Gene Symbol PAPPA