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p57 Kip2 Antibody (SR2016)

Images

 
Immunocytochemistry/ Immunofluorescence: p57 Kip2 Antibody (SR2016) [NBP3-21646] - Immunofluorescent analysis of HeLa cells treated with dexamethasone, using NBP3-21646.
Western Blot: p57 Kip2 Antibody (SR2016) [NBP3-21646] - Western blot analysis on HeLa cell using NBP3-21646.
Immunohistochemistry: p57 Kip2 Antibody (SR2016) [NBP3-21646] - Immunohistochemical analysis of paraffin-embedded rat kidney, using NBP3-21646.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IP
Clone
SR2016
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

p57 Kip2 Antibody (SR2016) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human p57 Kip2 (Uniprot #: P49918)
Specificity
Detects endogenous levels of total p57 Kip2
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
CDKN1C
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Immunoprecipitation 1:50
  • Western Blot 1:500-1:2000
Theoretical MW
57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for p57 Kip2 Antibody (SR2016)

  • Beckwith-Wiedemann syndrome
  • BWS
  • cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • cyclin-dependent kinase inhibitor 1C
  • Cyclin-dependent kinase inhibitor p57
  • KIP2BWCR
  • p57
  • p57Kip2
  • WBS

Background

p57kip2 is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for p57 Kip2 Antibody (NBP3-21646) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CDKN1C