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p53R2 Antibody Pair [HRP]

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Sandwich ELISA: p53R2 Antibody Pair [HRP] [NBP2-79410] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Sandwich ELISA: p53R2 Antibody Pair [HRP] [NBP2-79410] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP
Standard Curve Range
46.88-3000 pg/ml (example only; lot dependent)
Sensitivity
47 pg/ml (example only; lot dependent)

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
HRP
NBP2-79410-5Plates
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p53R2 Antibody Pair [HRP] Summary

Description
Solid Phase sandwich ELISA for the quantitative determination of Human p53R2.
Specificity
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Human p53R2.
Standard Curve Range
46.88-3000 pg/ml (example only; lot dependent)
Sensitivity
47 pg/ml (example only; lot dependent)
Assay Type
Sandwich ELISA
Sample Volume
100 ul
Gene
RRM2B

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  1. Mouse Monoclonal Capture Antibody
  2. Mouse Monoclonal Detection Antibody (HRP-conjugated)
  3. Standard

Alternate Names for p53R2 Antibody Pair [HRP]

  • EC 1.17.4.1
  • MGC102856
  • MGC42116
  • MTDPS8A
  • MTDPS8B
  • p53-inducible ribonucleotide reductase small subunit 2 homolog
  • p53-inducible ribonucleotide reductase small subunit 2-like protein
  • p53R2
  • P53R2DKFZp686M05248
  • PEOA5
  • ribonucleoside-diphosphate reductase subunit M2 B
  • ribonucleotide reductase M2 B (TP53 inducible)
  • RRM2B
  • TP53-inducible ribonucleotide reductase M2 B

Background

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and g-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumour suppression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol RRM2B