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OCRL Antibody

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Genetic Strategies: Western Blot: OCRL Antibody [NBP1-80973] - Analysis in EFO-21 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-OCRL antibody. Remaining relative ...read more
Immunohistochemistry-Paraffin: OCRL Antibody [NBP1-80973] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: OCRL Antibody [NBP1-80973] - Staining of human Fallopian tube shows moderate to strong cytoplasmic and membranous positivity in glandular cells.
Immunohistochemistry-Paraffin: OCRL Antibody [NBP1-80973] - Staining of human liver shows weak positivity in hepatocytes.
Immunohistochemistry-Paraffin: OCRL Antibody [NBP1-80973] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic and endothelial cells.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, KD
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
     

Genetic Strategies

   

Order Details

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OCRL Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: DYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELY
Predicted Species
Mouse (97%), Rat (99%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
OCRL
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
  • Knockdown Validated
  • Western Blot 0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
OCRL Protein (NBP1-80973PEP)
Publications
Read Publication using NBP1-80973.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for OCRL Antibody

  • EC 3.1.3.36
  • INPP5F
  • LOCR
  • Lowe oculocerebrorenal syndrome protein
  • NPHL2
  • OCRL1inositol polyphosphate 5-phosphatase OCRL-1
  • oculocerebrorenal syndrome of Lowe
  • phosphatidylinositol polyphosphate 5-phosphatase

Background

OCRL encodes a phosphatase enzyme that is involved in actin polymerization and is found in the trans-Golgi network. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for OCRL Antibody (NBP1-80973)(1)

Reviews for OCRL Antibody (NBP1-80973) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol OCRL
Entrez
Uniprot