NOB1 Antibody

In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publication 1 - 1 of 1.

Publication using NBP2-19558	Applications	Species
Blanca Nieto, Sonia G. Gaspar, Giulia Moriggi, Dimitri G. Pestov, Xosé R. Bustelo, Mercedes Dosil Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis Nature Communications 2020-01-09 [PMID: 31919354]

Array NBP2-19558

• NOB1 Antibodies
• NOB1 Lysate
• NOB1 Proteins