NGFR/TNFRSF16/p75NTR Antibody (74902) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

NGF R is a type I transmembrane protein that belongs to the tumor necrosis factor receptor family (1) and has been designated TNFRSF16. This receptor is also known as p75 NTR (neurotrophin receptor) because of its ability to bind at low affinity not only to NGF, but also other neurotrophins including Brain-Derived Neurotrophic Factor (BDNF), Neurotrophin-3 and Neurotrophin-4/5. NGF R is a 75 kDa protein that is expressed in neuronal axons, Schwann’s cells and perineural cells of peripheral nerves (1). Neural crest stem cells have been isolated based on their surface expression of NGF R (2, 3). In addition, neuroepithelial-derived NGF R positive cells have also been demonstrated to be able to differentiate into neurons, smooth muscle and Schwann cells in culture (4). NGF R has been used as a marker to identify mesenchymal precursors as well as hepatic stellate cells (5, 6).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 5 applications: Flow Cytometry, ICC, IHC, IHC-Fr, IHC-P.

Showing Publications 1 - 10 of 11. Show All 11 Publications. Collapse Publications.

Publications using MAB367	Applications	Species
Li H, Bräunig S, Dhapolar P et al. Identification of phenotypically, functionally, and anatomically distinct stromal niche populations in human bone marrow based on single-cell RNA sequencing eLife 3/6/2023 [PMID: 36876630]
Ajay Matta, Muhammad Zia Karim, Hoda Gerami, Bettina Zoe Benigno, Ivan Cheng, Arne Mehrkens et al. A Single Injection of NTG-101 Reduces the Expression of Pain-Related Neurotrophins in a Canine Model of Degenerative Disc Disease International Journal of Molecular Sciences 5/20/2022 [PMID: 35628530]
Sidorov MS, Kim H, Rougie M et al. Visual Sequences Drive Experience-Dependent Plasticity in Mouse Anterior Cingulate Cortex Cell Reports 9/15/2020 [PMID: 32937128]
Sidorov MS, Kim H, Rougie M et al. Visual Sequences Drive Experience-Dependent Plasticity in Mouse Anterior Cingulate Cortex Cell Reports 2020-09-15 [PMID: 32937128]
J Wang, A Wuethrich, AA Sina, RE Lane, LL Lin, Y Wang, J Cebon, A Behren, M Trau Tracking extracellular vesicle phenotypic changes enables treatment monitoring in melanoma Sci Adv, 2020-02-26;6(9):eaax3223. 2020-02-26 [PMID: 32133394] (Flow Cytometry, Human)	Flow Cytometry	Human
Rump L, Mattey D, Kehoe O, Middleton J An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium. Cytokine, 2017-09-01;97(0):133-140. 2017-09-01 [PMID: 28648867] (IHC-Fr, Human)	IHC-Fr	Human
Decreased demand for olfactory periglomerular cells impacts on neural precursor cell viability in the rostral migratory stream Sci Rep, 2016-08-30;6(0):32203. 2016-08-30 [PMID: 27573347] (IHC, Mouse)	IHC	Mouse
Xi R, Zhang X, Chen X, Pan S, Hui B, Zhang L, Fu S, Li X, Zhang X, Gong T, Guo J, Che S Human papillomavirus 16 infection predicts poor outcome in patients with esophageal squamous cell carcinoma. Onco Targets Ther, 2015-03-05;8(0):573-81. 2015-03-05 [PMID: 25784817] (IHC-P, Human)	IHC-P	Human
Strang CE, Renna JM, Amthor FR, Keyser KT. Muscarinic acetylcholine receptor localization and activation effects on ganglion response properties. Invest Ophthalmol Vis Sci 5/1/2010 [PMID: 20042645]
Berzi A, Ayata CK, Cavalcante P, Falcone C, Candiago E, Motta T, Bernasconi P, Hohlfeld R, Mantegazza R, Meinl E, Farina C BDNF and its receptors in human myasthenic thymus: implications for cell fate in thymic pathology. J. Neuroimmunol., 2008-06-13;197(2):128-39. 2008-06-13 [PMID: 18555538] (ICC, IHC-Fr, Human)	ICC, IHC-Fr	Human
Garderet L, Mazurier C, Chapel A, Ernou I, Boutin L, Holy X, Gorin NC, Lopez M, Doucet C, Lataillade JJ Mesenchymal stem cell abnormalities in patients with multiple myeloma. Leuk. Lymphoma, 2007-10-01;48(10):2032-41. 2007-10-01 [PMID: 17917971] (Flow Cytometry, Human)	Flow Cytometry	Human
Show All 11 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Verified Customer	ICC	Human	02/25/2022	View Summary Application Immunocytochemistry Sample Tested primary astrocytes Species Human Lot GUC0319081
Enlarge	4 reviewed by: Christian Schuerch	IHC-Fr	Human	02/29/2020	View Summary Application Immunohistochemistry-Frozen Sample Tested human tonsil Species Human Lot N/A Comments Comments pH 9 epitope retrieval

Array MAB367

• NGFR/TNFRSF16/p75NTR Antibodies
• NGFR/TNFRSF16/p75NTR Lysate
• NGFR/TNFRSF16/p75NTR Proteins
• NGFR/TNFRSF16/p75NTR Proteins and Enzymes
• NGFR/TNFRSF16/p75NTR ELISAs