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Neuropilin-1 Antibody (130604) [DyLight 488]

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB, IHC
Clone
130604
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB5661U
Alexa Fluor 405
FAB5661V-100UG
Alexa Fluor 488
FAB5661G-100UG
Alexa Fluor 532
FAB5661X
Alexa Fluor 594
FAB5661T
Alexa Fluor 647
FAB5661R-100UG
Alexa Fluor 700
FAB5661N-100UG
Alexa Fluor 750
FAB5661S-100UG
Allophycocyanin
FAB5661A
Biotin
FAB5661B
DyLight 350
FAB5661D
DyLight 405
FAB5661E
DyLight 550
FAB5661L
DyLight 594
FAB5661M
DyLight 650
FAB5661W
DyLight 680
FAB5661Y
DyLight 755
FAB5661Z
FITC
FAB5661F
HRP
FAB5661H
Janelia Fluor 525
FAB5661JF525
Janelia Fluor 549
FAB5661I
Janelia Fluor 585
FAB5661JF585
Janelia Fluor 635
FAB5661JF635
Janelia Fluor 646
FAB5661J
Janelia Fluor 669
FAB5661JF669
PE
FAB5661P
PerCP
FAB5661C
Unconjugated
MAB5661
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB5661
Carrier Free
MAB5661
Carrier Free
MAB5661-SP
Carrier Free
FAB5661V-100UG
Carrier Free
FAB5661S-100UG
Carrier Free
FAB5661R-100UG
Carrier Free
FAB5661N-100UG
Carrier Free
FAB5661G-100UG
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Neuropilin-1 Antibody (130604) [DyLight 488] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant rat Neuropilin‑1
Met1-Asp854 (Lys811Arg, Pro812-Gly828 del), predicted
Accession # Q9QWJ9
Specificity
Detects rat Neuropilin-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant rat Neuropilin-2 is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NRP1
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Neuropilin-1 Antibody (130604) [DyLight 488]

  • BDCA4
  • BDCA-4
  • CD304 antigen
  • CD304
  • DKFZp686A03134
  • DKFZp781F1414
  • neuropilin 1
  • Neuropilin1
  • Neuropilin-1
  • NP1
  • NRP
  • NRP1
  • transmembrane receptor
  • Vascular endothelial cell growth factor 165 receptor
  • VEGF165R

Background

Neuropilin-1/CD304 is a type-I transmembrane protein. It forms a heterodimeric complex with vascular endothelial growth factor receptor 2, and this complex functions as a receptor for vascular endothelial growth factor. On the other hand, Neuropilin-1/CD304 forms a complex with plexin-1, and this complex acts as a semaphorin 3A receptor. Neuropilin-1/CD304 is involved in angiogenesis, axon guidance, cell survival, migration, and invasion. Recently, it has been reported that Neuropilin-1/CD304 is an essential component located on the immunological synapse and acts as a potent cell-surface marker for murine regulatory T cells (Treg). Neuropilin-1/CD304 expressed by Treg cells promotes long interactions between Treg cells and immature dendritic cells and restricts access of effector cells to the antigen-presenting cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Neuropilin-1
Antibody (130604) [Dy ...
FAB5661K
Neuropilin-1 Antibody (130604) [DyLight 488]
Species: Rt
Applications: WB, IHC

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Product General Protocols

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FAQs for Neuropilin-1 Antibody (FAB5661K). (Showing 1 - 2 of 2 FAQ).

  1. If this product is used in an application or species as a part of a customer review, will that validate this product in the application/species?
    • If any of our primary antibodes are used in an untested application or species and it is shown to work through images from customer reviews or through publications, this validates the application/species for this product. Please check out our Innovator's Reward Program if you decide to test an antibody with a species or application that is not currently listed.
  2. What research areas can Neuropilin-1 antibodies be used in?
    • Neuropilin-1 products can be applied in the following research areas: Adaptive Immunity, Angiogenesis, Breast Cancer, Cancer, Cardiovascular Biology, Neuroscience, and Virology Bacteria and Parasites.

Secondary Antibodies

 

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Bioinformatics

Gene Symbol NRP1