| Reactivity | RtSpecies Glossary |
| Applications | WB |
| Clonality | Polyclonal |
| Host | Sheep |
| Conjugate | Biotin |
| Concentration | LYOPH |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant rat Neurexin 1 beta isoform 1 Ala47-Thr392 Accession # Q63373 |
| Specificity | Detects rat Neurexin 1 beta in Western blots. In Western blots, approximately 25% cross-reactivity with recombinant rat Neurexin 1 alpha is observed. |
| Source | N/A |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Sheep |
| Gene | Nrxn1 |
| Purity Statement | Antigen Affinity-purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
| Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. |
| Preservative | No Preservative |
| Concentration | LYOPH |
| Reconstitution Instructions | Reconstitute at 0.2 mg/mL in sterile PBS. |
Neurexin 1 beta is an 80 kDa member of the Neurexin family of proteins. It is expressed on neuronal presynaptic membranes and contributes to synapse formation through binding to postsynaptic neuroligins. An alternate start site in the Neurexin 1 gene generate an alpha - (long) and beta - (short) isoform. Mature rat Neurexin 1 beta is a type I transmembrane glycoprotein that is 468 amino acids (aa) in length. It has a 346 aa extracellular region (aa 47‑392) that contains one laminin-like G domain (aa 91‑264). Within the G domain, the presence or absence of a splice site (aa 201‑230) materially impacts neuroligin binding. Over aa 47‑392, rat Neurexin 1 beta is 100% and 98% aa identical to mouse and human Neurexin 1 beta , respectively.
Secondary Antibodies |
Isotype Controls |
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![Immunohistochemistry Neurexin 3/NRXN3 Antibody [Unconjugated]](https://images.novusbio.com/images2/af5269_human-mouse-neurexin-3-affinity-purified-polyclonal-ab-immunohistochemistry-2682022134435.jpg)
![Western Blot Neurexin 3/NRXN3 Antibody [Unconjugated]](https://images.novusbio.com/images/antibody/af5269_human-mouse-neurexin-3-affinity-purified-polyclonal-ab-western-blot-612023112046.jpg)
![Immunohistochemistry Neuroligin 4X/NLGN4X Antibody [Unconjugated]](https://images.novusbio.com/images2/Neuroligin_4_AF5158_Immunohistochemistry_10637.jpg)
![Western Blot Neuroligin 4X/NLGN4X Antibody [Unconjugated]](https://images.novusbio.com/images2/Neuroligin_4_AF5158_Western_Blot_5643.jpg)
