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Neuregulin-1/NRG1 Antibody [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin
Concentration
LYOPH

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Catalog# & Conjugate Size Price
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Neuregulin-1/NRG1 Antibody [Biotin] Summary

Immunogen
E. coli-derived recombinant human Neuregulin‑1/NRG1 Isoform GGF2
Gly51-Cys248
Accession # NP_039256
Specificity
Detects human Neuregulin‑1/NRG1 Isoform GGF2 in Western blots.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
NRG1
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Neuregulin-1/NRG1 Antibody [Biotin]

  • ARIA
  • GGF2
  • GGFglial growth factor
  • Heregulin-1
  • HGL
  • HGLneu differentiation factor
  • HRG
  • HRG1
  • HRG1-alpha
  • HRG1-beta 1
  • HRGAneuregulin 1 type IV beta 1a
  • MST131
  • MSTP131
  • NDFheregulin, alpha (45kD, ERBB2 p185-activator)
  • neuregulin 1 type IV beta 3
  • neuregulin 1
  • Neuregulin1
  • Neuregulin-1
  • NRG1
  • pro-neuregulin-1, membrane-bound isoform
  • pro-NRG1
  • sensory and motor neuron derived factor
  • SMDF

Background

By alternative splicing, the Neuregulin 1 gene ecodes at least 10 secreted or membrane-bound proteins, all of which contain an EGF-like domain. Neuregulin 1 isoforms bind and signal via the ErbB family of receptor tyrosine kinases. Isoform GGF2 contains a unique kringle-like domain, plus Ig and EGF-like domains that are also present in multiple Neuregulin 1 isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NRG1
Uniprot