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N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibody

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Immunohistochemistry-Paraffin: N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibody [NBP2-37978] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: YEPVLLAKTRSSESIPHLGADAGLHAALHATVVQ
Predicted Species
Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NDST1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
N-Deacetylase/N-Sulfotransferase 1/NDST1 Protein (NBP2-37978PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibody

  • [Heparan sulfate]-glucosamine N-sulfotransferase 1
  • bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
  • EC 2.8.2.8
  • Glucosaminyl N-deacetylase/N-sulfotransferase 1
  • heparan sulfate-N-deacetylase/N-sulfotransferase
  • HSNST 1
  • HSNST1
  • HSST1
  • HSSTN-HSST 1
  • N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
  • NDST1
  • NDST-1
  • N-heparan sulfate sulfotransferase 1
  • NST1

Background

Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine(GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backboneto make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a rolein determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence isabsolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands,thereby playing a role in inflammatory response

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NDST1
Uniprot