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Myosin VIIa Antibody (31A12)

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Flow Cytometry: Myosin VIIa Antibody (31A12) [NBP3-26121] - Overlay Peak curve showing HepG2 cells stained with Myosin VIIa Antibody (31A12) (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow
Clone
31A12
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Myosin VIIa Antibody (31A12) Summary

Additional Information
Recombinant monoclonal antibody expressed in HEK293F cells
Immunogen
A synthesized peptide derived from Human Myosin VIIa [UniProt Q13402]
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
MYO7A
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry 1:50-1:200

Packaging, Storage & Formulations

Storage
Store at -20 to -70C. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl and 50% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Myosin VIIa Antibody (31A12)

  • deafness, autosomal dominant 11
  • deafness, autosomal recessive 2
  • DFNA11
  • DFNB2
  • myosin VIIA
  • myosin-VIIa
  • MYOVIIA
  • MYU7A
  • USH1Bsevere))

Background

Myosin VIIa is a member of the myosin superfamily of actin-based motor proteins. Defects in the myosin VIIa gene are responsible for hearing impairment in shaker-1 (sh1) mice and causes Usher syndrome IB in humans. Usher syndrome associates congenital deafness, vestibular dysfunction, and retinitis pigmentosa and is the most common form of combined deafness and blindness. Structural features of myosin VIIa protein include an ATP binding N-terminal motor domain, a central region which possess five light-chain binding (IQ) motifs, and a C-terminal domain with three myosin tail homology (MyTH4) and talin-like homology regions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MYO7A