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Myosin Phosphatase Antibody [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-38889AF350
Alexa Fluor 405
NB110-38889AF405
Alexa Fluor 488
NB110-38889AF488
Alexa Fluor 532
NB110-38889AF532
Alexa Fluor 594
NB110-38889AF594
Alexa Fluor 647
NB110-38889AF647
Alexa Fluor 700
NB110-38889AF700
Alexa Fluor 750
NB110-38889AF750
Allophycocyanin
NB110-38889APC
Biotin
NB110-38889B
DyLight 350
NB110-38889UV
DyLight 405
NB110-38889V
DyLight 488
NB110-38889G
DyLight 550
NB110-38889R
DyLight 650
NB110-38889C
DyLight 680
NB110-38889FR
DyLight 755
NB110-38889IR
FITC
NB110-38889F
HRP
NB110-38889H
Janelia Fluor 549
NB110-38889JF549
Janelia Fluor 646
NB110-38889JF646
PE
NB110-38889PE
PerCP
NB110-38889PCP
Unconjugated
NB110-38889
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Myosin Phosphatase Antibody [DyLight 594] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 400 and 450 of human Myosin Phosphatase Target Subunit 1 (Protein Phosphatase 1, Regulatory Subunit 12A) using the numbering given in entry NP_002471.1
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PPP1R12A
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Myosin Phosphatase Antibody [DyLight 594]

  • MBSmyosin phosphatase, target subunit 1
  • MGC133042
  • Myosin phosphatase target subunit 1
  • Myosin phosphatase-targeting subunit 1
  • MYPT1protein phosphatase 1 regulatory subunit 12A
  • protein phosphatase 1, regulatory (inhibitor) subunit 12A
  • Protein phosphatase myosin-binding subunit

Background

The major protein phosphatase-1 (PP1) is composed of 3 subunits with apparent molecular mass of 110-130, 37 & 20 kDa. The 110-130 kDa component act as a regulatory subunit known as myosine binding (MBS) or myosine phosphatae targeting subunit (MYPT). The N-terminal portion of MYPT binds to both PP1c-delta and phosphorylated myosin, thereby increasing myosin phosphatase activity. Two isoform of MYPT have been identified (MYPT1 & MYPT2) and share 61% sequence identity. While MYPT1 is widely distributed in human tissues, MYPT2 is mostly detected in brain and heart.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PPP1R12A