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Myosin Light Chain 2 Antibody (F36.5B9)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
F36.5B9
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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Myosin Light Chain 2 Antibody (F36.5B9) Summary

Immunogen
Human ventricular myosin.
Specificity
Recognizes the S1/S2 junction of human ventricular myosin heavy chain beta-.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
MYL2
Purity
N/A
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Frozen
  • Western Blot
Application Notes
Immunohistochemistry (frozen sections): can be used undiluted.
Western Blot: dilution 1:10.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
N/A

Alternate Names for Myosin Light Chain 2 Antibody (F36.5B9)

  • cardiac ventricular myosin light chain 2
  • CMH10myosin light chain 2
  • DKFZp779C0562
  • MLC2
  • MLC-2
  • MLC-2v
  • myosin regulatory light chain 2, ventricular/cardiac muscle isoform
  • myosin, light chain 2, regulatory, cardiac, slow
  • myosin, light polypeptide 2, regulatory, cardiac, slow
  • regulatory light chain of myosin
  • RLC of myosin
  • slow cardiac myosin regulatory light chain 2

Background

MYL2 (myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MYL2