Myosin Light Chain 2 Antibody (F109.3E1) Summary
Immunogen |
Both human ventricular myosin light chains. |
Specificity |
Recognizes myosin light chain 2 (LC2) (aa 45-59). |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
MYL2 |
Purity |
N/A |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry-Frozen
- Western Blot
|
Application Notes |
Immunohistochemistry (frozen sections): can be used undiluted. Western Blot: dilution 1:10. |
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
Sterile filtered supernatant |
Preservative |
0.1% Sodium Azide |
Purity |
N/A |
Alternate Names for Myosin Light Chain 2 Antibody (F109.3E1)
Background
MYL2 (myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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