Myelin PLP Antibody

Chicken products cannot be exported to Canada.

Purification Notes
After repeated injections into the hens, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column, the concentration of the eluate adjusted to 100 ug/ml, and the preparation was filter sterilized.

Storage Notes
Store at 4C in the dark. Under these conditions, the antibodies should have a shelf life of at least 12 months (provided they remain sterile). Do not freeze these antibodies unless you want to store them for longer periods of time. Note, however, that each time an antibody preparation is frozen, about half of its binding activity is lost.

Human PLP (also known as lipophilin) is a 30 kDa protein (277 amino acids) found in myelin of the CNS and PNS. Expressed by oligodendrocytes and Schwann cells, PLP stabilizes myelin by preventing lipid bilayer fusion, and aids in compaction. Different mutations of the human PLP gene product result in two neurological disorders - Pelizaeus-Merzbacher disease and Spastic Paraplegia type 2.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: WB.

Showing Publications 1 - 2 of 2.

Publications using NB100-1608	Applications	Species
Nunes, D, Cruz, T L Et al. Mapping axonal density and average diameter using non-monotonic time-dependent gradient-echo MRI. J Magn Reson 2017-04-01 [PMID: 28282586] (WB, Human)	WB	Human
Cachon-Gonzalez MB, Wang SZ, Ziegler R et al. Reversibility of neuropathology in Tay-Sachs-related diseases. Hum Mol Genet. 2013-10-25 [PMID: 24057669] (WB, Mouse)	WB	Mouse

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Verified Customer	ICC	homo sapiens and Human	10/22/2021	View Summary Application Immunocytochemistry Sample Tested brain and spinal cord Species homo sapiens and Human Lot plp0305

Array NB100-1608

• Myelin PLP Antibodies
• Myelin PLP ELISA Kit
• Myelin PLP Lysates
• Myelin PLP Proteins