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Myelin PLP Antibody (plpc 1) [DyLight 755]

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Product Details

Summary
Reactivity Bv, MaSpecies Glossary
Applications WB, Flow, ICC/IF, IHC
Clone
plpc 1
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 755

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB600-960AF350
Alexa Fluor 405
NB600-960AF405-100ul
Alexa Fluor 488
NB600-960AF488-100ul
Alexa Fluor 532
NB600-960AF532
Alexa Fluor 594
NB600-960AF594
Alexa Fluor 647
NB600-960AF647-100ul
Alexa Fluor 700
NB600-960AF700-100ul
Alexa Fluor 750
NB600-960AF750
Allophycocyanin
NB600-960APC-100ul
Allophycocyanin/Cy7
NB600-960APCCY7
Biotin
NB600-960B
DyLight 350
NB600-960UV-100ul
DyLight 405
NB600-960V-100ul
DyLight 488
NB600-960G-100ul
DyLight 550
NB600-960R
DyLight 594
NB600-960DL594
DyLight 650
NB600-960C
DyLight 680
NB600-960FR-100ul
FITC
NB600-960F
HRP
NB600-960H
Janelia Fluor 549
NB600-960JF549
Janelia Fluor 646
NB600-960JF646
PE
NB600-960PE-100ul
PE/Atto594
NB600-960PEATT594
PE/Cy5.5
NB600-960PECY55
PE/Cy7
NB600-960PECY7
PerCP
NB600-960PCP-100ul
Unconjugated
NB600-960-0.1mg
mFluor Violet 450 SE
NB600-960MFV450
mFluor Violet 500 SE
NB600-960MFV500
mFluor Violet 610 SE
NB600-960MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB600-960-0.1mg
BSA Free
NB600-960
BSA Free
NB600-960-0.1mg
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Myelin PLP Antibody (plpc 1) [DyLight 755] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Synthetic peptide: C-GRGTKF, corresponding to amino acids 272-277 of Myelin PLP.
Marker
Oligodendrocyte Marker
Specificity
This recognizes myelin proteolipid protein.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
PLP1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Myelin PLP Antibody (plpc 1) [DyLight 755]

  • DM-20
  • HLD1
  • Lipophilin
  • major myelin proteolipid protein
  • MMPL
  • Myelin PLP
  • myelin proteolipid protein
  • PLP
  • PLP/DM20
  • PLP1
  • PMD
  • proteolipid protein 1
  • spastic paraplegia 2, uncomplicated
  • SPG2

Background

Human PLP (also known as lipophilin) is a 30 kDa protein (277 amino acids) found in myelin of the CNS and PNS. Expressed by oligodendrocytes and Schwann cells, PLP stabilizes myelin by preventing lipid bilayer fusion, and aids in compaction. Different mutations of the human PLP gene product result in two neurological disorders - Pelizaeus-Merzbacher disease and Spastic Paraplegia type 2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PLP1