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Myelin PLP Antibody (PLP1/4259) [DyLight 755]

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Flow Cytometry: Myelin PLP Antibody (PLP1/4259) [DyLight 755] [NBP3-08534IR] - Total extracellular vesicles with Myelin PLP Antibody (PLP1/4259) [Alexa Fluor® 647] (Catalog # NBP3-08534AF647) (left). Gate determined vesicles positive for PLP1 antibody ranging from 500-800nm size. Image on the right represents the same sample without antibody. 10ul of pre-isolated extracellular vesicles were incubated with 2ul of Myelin PLP Antibody (PLP1/4259) [Alexa Fluor® 647] , during 20 minutes at room temperature, and analyzed in nanoscale flow cytometer able to resolve particles scattering as little as 100um. Image from a verified customer review.
Flow Cytometry: Myelin PLP Antibody (PLP1/4259) [DyLight 755] [NBP3-08534IR] - Total extracellular vesicles with Myelin PLP Antibody (PLP1/4259) [Alexa Fluor® 647] (Catalog # NBP3-08534AF647) (left). Gate ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, ReSpecies Glossary
Applications Flow, IHC
Clone
PLP1/4259
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 755

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-08534AF350
Alexa Fluor 405
NBP3-08534AF405
Alexa Fluor 488
NBP3-08534AF488
Alexa Fluor 532
NBP3-08534AF532
Alexa Fluor 594
NBP3-08534AF594
Alexa Fluor 647
NBP3-08534AF647
Alexa Fluor 700
NBP3-08534AF700
Alexa Fluor 750
NBP3-08534AF750
Allophycocyanin
NBP3-08534APC
Biotin
NBP3-08534B
CoraFluor 1
NBP3-08534CL1
DyLight 350
NBP3-08534UV
DyLight 405
NBP3-08534V
DyLight 488
NBP3-08534G
DyLight 550
NBP3-08534R
DyLight 594
NBP3-08534DL594
DyLight 650
NBP3-08534C
DyLight 680
NBP3-08534FR
FITC
NBP3-08534F
HRP
NBP3-08534H
Janelia Fluor 525
NBP3-08534JF525
Janelia Fluor 549
NBP3-08534JF549
Janelia Fluor 585
NBP3-08534JF585
Janelia Fluor 635
NBP3-08534JF635
Janelia Fluor 646
NBP3-08534JF646
Janelia Fluor 669
NBP3-08534JF669
PE
NBP3-08534PE
PerCP
NBP3-08534PCP
Unconjugated
NBP3-07603-100ug
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-07603-100ug
Azide and BSA Free
NBP3-08534
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Myelin PLP Antibody (PLP1/4259) [DyLight 755] Summary

Immunogen
Synthetic peptide GRGTKF that recognizes the C terminal region (aa272-277) of Myelin PLP protein. (Uniprot: P60201)
Localization
Membrane
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
PLP1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry Validated for Flow Cytometry from a verified customer review.
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Tenerife Lizard

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Myelin PLP Antibody (PLP1/4259) [DyLight 755]

  • DM-20
  • HLD1
  • Lipophilin
  • major myelin proteolipid protein
  • MMPL
  • Myelin PLP
  • myelin proteolipid protein
  • PLP
  • PLP/DM20
  • PLP1
  • PMD
  • proteolipid protein 1
  • spastic paraplegia 2, uncomplicated
  • SPG2

Background

Human PLP (also known as lipophilin) is a 30 kDa protein (277 amino acids) found in myelin of the CNS and PNS. Expressed by oligodendrocytes and Schwann cells, PLP stabilizes myelin by preventing lipid bilayer fusion, and aids in compaction. Different mutations of the human PLP gene product result in two neurological disorders - Pelizaeus-Merzbacher disease and Spastic Paraplegia type 2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PLP1