Home » Muscle Phosphofructokinase/PFKM/PFK-1 » PFK-1 Antibodies » Muscle Phosphofructokinase/PFKM/PFK-1 Antibody (2F11) [mFluor Violet 500 SE]
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Muscle Phosphofructokinase/PFKM/PFK-1 Antibody (2F11) [mFluor Violet 500 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
2F11
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 500 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-22615AF350
Alexa Fluor 405
NBP2-22615AF405
Alexa Fluor 488
NBP2-22615AF488
Alexa Fluor 532
NBP2-22615AF532
Alexa Fluor 594
NBP2-22615AF594
Alexa Fluor 647
NBP2-22615AF647
Alexa Fluor 700
NBP2-22615AF700
Alexa Fluor 750
NBP2-22615AF750
Biotin
NBP2-22615B
CoraFluor 1
NBP2-22615CL1
DyLight 350
NBP2-22615UV
DyLight 405
NBP2-22615V
DyLight 488
NBP2-22615G
DyLight 550
NBP2-22615R
DyLight 594
NBP2-22615DL594
DyLight 650
NBP2-22615C
DyLight 680
NBP2-22615FR
DyLight 755
NBP2-22615IR
FITC
NBP2-22615F
HRP
NBP2-22615H
Janelia Fluor 525
NBP2-22615JF525
Janelia Fluor 549
NBP2-22615JF549
Janelia Fluor 646
NBP2-22615JF646
Janelia Fluor 669
NBP2-22615JF669
Unconjugated
NBP2-22615
mFluor Violet 450 SE
NBP2-22615MFV450
mFluor Violet 610 SE
NBP2-22615MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-22615
BSA Free
NBP2-22615
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Muscle Phosphofructokinase/PFKM/PFK-1 Antibody (2F11) [mFluor Violet 500 SE] Summary

Immunogen
Recombinant human Muscle Phosphofructokinase/PFKM/PFK-1(1-780aa) purified from E. coli
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PFKM
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Muscle Phosphofructokinase/PFKM/PFK-1 Antibody (2F11) [mFluor Violet 500 SE]

  • 6-phosphofructokinase, muscle type
  • EC 2.7.1,6-phosphofructo-1-kinase
  • EC 2.7.1.11
  • GSD7
  • MGC8699
  • Muscle Phosphofructokinase
  • PFK1
  • PFK-1
  • PFKA
  • PFK-A
  • PFKM
  • PFKX
  • Phosphofructo-1-kinase isozyme A
  • Phosphofructokinase 1
  • phosphofructokinase, muscle
  • phosphofructokinase, polypeptide X
  • Phosphofructokinase-1
  • Phosphofructokinase-M
  • Phosphohexokinase

Background

Phosphofructokinases (PFK) are regulatory glycolytic enzymes that convert fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. Human PFK-1 is tetrameric and isoenzymes include PFK-1 muscle (PFKM, PFK-A), PFK-1 liver (PFKL, PFK-B) and PFK-1 platelet (PFKP, PFK-C, PFKF). PFK-1 is inhibited by ATP and citrate (from the tricarboxylic acid cycle). PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose 2,6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regulator for PFK-1. PFK-2 catalyzes the synthesis of fructose 2,6-bisphosphate and contains fructose 2,6-biphosphatase activity that catalyzes the degradation of fructose 2,6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, inducible PFK-2) and PFK-2 testis (PFKFB4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PFKM