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MUL1 Antibody (5H6.2D5) [mFluor Violet 500 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
5H6.2D5
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 500 SE

Order Details

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MUL1 Antibody (5H6.2D5) [mFluor Violet 500 SE] Summary

Immunogen
Partial recombinant protein made to a C-terminal portion of the human MUL1 protein (between residues 200-352) [UniProt Q969V5]
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MUL1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

The immunogen sequence shows 99% similarity to Monkey's MUL1 and is 84% similar to isoform 1 and 3 of Mouse's MUL1 .

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MUL1 Antibody (5H6.2D5) [mFluor Violet 500 SE]

  • C1orf166mitochondrial E3 ubiquitin ligase 1
  • E3 ubiquitin-protein ligase MUL1
  • EC 6.3.2
  • EC 6.3.2.-
  • FLJ12875
  • GIDERP11-401M16.2
  • Growth inhibition and death E3 ligase
  • MAPLE3 ubiquitin ligase
  • mitochondrial E3 ubiquitin protein ligase 1
  • mitochondrial ubiquitin ligase activator of NFKB 1
  • mitochondrial ubiquitin ligase activator of NF-kB
  • Mitochondrial-anchored protein ligase
  • MULANchromosome 1 open reading frame 166
  • Putative NF-kappa-B-activating protein 266
  • RING finger protein 218
  • RNF218mitochondria-anchored protein ligase

Background

E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotesmitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed,activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin froman E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targetedsubstrates

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for MUL1 Antibody (NBP2-31361MFV500) (0)

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Secondary Antibodies

 

Isotype Controls

Additional MUL1 Products

Array NBP2-31361MFV500

Research Areas for MUL1 Antibody (NBP2-31361MFV500)

Find related products by research area.

Blogs on MUL1.

MUL1 - A Mito's best friend
MUL1 is an E3 ubiquitin-protein ligase with a RING finger domain that controls mitochondrial morphology, fragmentation and localization. E3 ubiquitin ligases accept the component ubiquitin from a donor E2 ubiquitin-conjugating directly transfer this u...  Read full blog post.

mFluor Violet Conjugated Antibodies

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Bioinformatics

Gene Symbol MUL1