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MUL1 Antibody (3G2.2F7) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB, IHC
Clone
3G2.2F7
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-31362AF350
Alexa Fluor 405
NBP2-31362AF405
Alexa Fluor 488
NBP2-31362AF488
Alexa Fluor 532
NBP2-31362AF532
Alexa Fluor 594
NBP2-31362AF594
Alexa Fluor 647
NBP2-31362AF647
Alexa Fluor 700
NBP2-31362AF700
Alexa Fluor 750
NBP2-31362AF750
Allophycocyanin
NBP2-31362APC
Biotin
NBP2-31362B
CoraFluor 1
NBP2-31362CL1
DyLight 350
NBP2-31362UV
DyLight 405
NBP2-31362V
DyLight 488
NBP2-31362G
DyLight 550
NBP2-31362R
DyLight 594
NBP2-31362DL594
DyLight 650
NBP2-31362C
DyLight 680
NBP2-31362FR
DyLight 755
NBP2-31362IR
FITC
NBP2-31362F
HRP
NBP2-31362H
Janelia Fluor 525
NBP2-31362JF525
Janelia Fluor 585
NBP2-31362JF585
Janelia Fluor 635
NBP2-31362JF635
Janelia Fluor 646
NBP2-31362JF646
Janelia Fluor 669
NBP2-31362JF669
PE
NBP2-31362PE
PerCP
NBP2-31362PCP
Unconjugated
NBP2-31362-0.1mg
mFluor Violet 450 SE
NBP2-31362MFV450
mFluor Violet 500 SE
NBP2-31362MFV500
mFluor Violet 610 SE
NBP2-31362MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-31362-0.1mg
BSA Free
NBP2-31362-0.025mg
BSA Free
NBP2-31362-0.1mg
Azide and BSA Free
NBP2-80861
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MUL1 Antibody (3G2.2F7) [Janelia Fluor® 549] Summary

Immunogen
Partial recombinant protein made to a C-terminal portion of the human MUL1 protein (between residues 200-352) [UniProt Q969V5]
Localization
Mitochondria, Peroxisomes
Predicted Species
Primate (99%). Backed by our 100% Guarantee.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MUL1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

The immunogen sequence shows 99% similarity to Monkey's MUL1 and is 84% similar to isoform 1 and 3 of Mouse's MUL1 .

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for MUL1 Antibody (3G2.2F7) [Janelia Fluor® 549]

  • C1orf166mitochondrial E3 ubiquitin ligase 1
  • E3 ubiquitin-protein ligase MUL1
  • EC 6.3.2
  • EC 6.3.2.-
  • FLJ12875
  • GIDERP11-401M16.2
  • Growth inhibition and death E3 ligase
  • MAPLE3 ubiquitin ligase
  • mitochondrial E3 ubiquitin protein ligase 1
  • mitochondrial ubiquitin ligase activator of NFKB 1
  • mitochondrial ubiquitin ligase activator of NF-kB
  • Mitochondrial-anchored protein ligase
  • MULANchromosome 1 open reading frame 166
  • Putative NF-kappa-B-activating protein 266
  • RING finger protein 218
  • RNF218mitochondria-anchored protein ligase

Background

E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotesmitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed,activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin froman E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targetedsubstrates

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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MUL1 is an E3 ubiquitin-protein ligase with a RING finger domain that controls mitochondrial morphology, fragmentation and localization. E3 ubiquitin ligases accept the component ubiquitin from a donor E2 ubiquitin-conjugating directly transfer this u...  Read full blog post.
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Bioinformatics

Gene Symbol MUL1