Mouse VEGFR2/Flk-1 Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

Showing Publications 1 - 10 of 14. Show All 14 Publications. Collapse Publications.

Publications using MVR200B	Applications	Species
M Mastri, CR Lee, A Tracz, RS Kerbel, M Dolan, Y Shi, JML Ebos Tumor-independent host secretomes induced by angiogenesis and immune-checkpoint inhibitors Mol. Cancer Ther., 2018-04-25;0(0):. 2018-04-25 [PMID: 29695634] (Mouse)		Mouse
CM Medeiros D, V Perugini, P Bernegger, M Centola, A Barbero, AL Guildford, M Santin, A Banfi, I Martin, A Marsano Vascular Endothelial Growth Factor Sequestration Enhances In Vivo Cartilage Formation Int J Mol Sci, 2017-11-21;18(11):. 2017-11-21 [PMID: 29160845] (Human)		Human
C Di Mauro, R Rosa, V D'Amato, P Ciciola, A Servetto, R Marciano, RC Orsini, L Formisano, S De Falco, V Cicatiello, M Di Bonito, M Cantile, F Collina, A Chambery, BM Veneziani, S De Placido, R Bianco Hedgehog signalling pathway orchestrates angiogenesis in triple-negative breast cancers Br. J. Cancer, 2017-04-25;0(0):. 2017-04-25 [PMID: 28441382] (Human, Mouse)		Human, Mouse
Howell KR, Kutiyanawalla A, Pillai A Long-term continuous corticosterone treatment decreases VEGF receptor-2 expression in frontal cortex. PLoS ONE, 2011-05-27;6(5):e20198. 2011-05-27 [PMID: 21647420] (Mouse)		Mouse
Ruiz de Almodovar C, Coulon C, Salin PA, Knevels E, Chounlamountri N, Poesen K, Hermans K, Lambrechts D, Van Geyte K, Dhondt J, Dresselaers T, Renaud J, Aragones J, Zacchigna S, Geudens I, Gall D, Stroobants S, Mutin M, Dassonville K, Storkebaum E, Jordan BF, Eriksson U, Moons L, D'Hooge R, Haigh JJ, Belin MF, Schiffmann S, Van Hecke P, Gallez B, Vinckier S, Chedotal A, Honnorat J, Thomasset N, Carmeliet P, Meissirel C Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1. J. Neurosci., 2010-11-10;30(45):15052-66. 2010-11-10 [PMID: 21068311] (Mouse)		Mouse
Satofuka S, Ichihara A, Nagai N, Noda K, Ozawa Y, Fukamizu A, Tsubota K, Itoh H, Oike Y, Ishida S (Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system. Am. J. Pathol., 2008-10-30;173(6):1911-8. 2008-10-30 [PMID: 18974301] (Mouse)		Mouse
Izumi-Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, Ohno S, Oike Y, Ishida S Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin. Invest. Ophthalmol. Vis. Sci., 2008-04-01;49(4):1679-85. 2008-04-01 [PMID: 18385091] (Mouse)		Mouse
Xie B, Shen J, Dong A, Swaim M, Hackett SF, Wyder L, Worpenberg S, Barbieri S, Campochiaro PA An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization. FASEB J., 2008-04-01;22(8):2775-83. 2008-04-01 [PMID: 18381816] (Mouse)		Mouse
Ebos JM, Lee CR, Bogdanovic E, Alami J, Van Slyke P, Francia G, Xu P, Mutsaers AJ, Dumont DJ, Kerbel RS Vascular endothelial growth factor-mediated decrease in plasma soluble vascular endothelial growth factor receptor-2 levels as a surrogate biomarker for tumor growth. Cancer Res., 2008-01-15;68(2):521-9. 2008-01-15 [PMID: 18199548] (Mouse)		Mouse
Ebos JM, Lee CR, Christensen JG, Mutsaers AJ, Kerbel RS Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy. Proc. Natl. Acad. Sci. U.S.A., 2007-10-17;104(43):17069-74. 2007-10-17 [PMID: 17942672] (Mouse)		Mouse
Shimojo N, Jesmin S, Zaedi S, Otsuki T, Maeda S, Yamaguchi N, Aonuma K, Hattori Y, Miyauchi T Contributory role of VEGF overexpression in endothelin-1-induced cardiomyocyte hypertrophy. Am. J. Physiol. Heart Circ. Physiol., 2007-03-16;293(1):H474-81. 2007-03-16 [PMID: 17369464] (Rat)		Rat
Iemitsu M, Maeda S, Jesmin S, Otsuki T, Miyauchi T Exercise training improves aging-induced downregulation of VEGF angiogenic signaling cascade in hearts. Am. J. Physiol. Heart Circ. Physiol., 2006-04-14;291(3):H1290-8. 2006-04-14 [PMID: 16617130] (Rat)		Rat
Nagai N, Noda K, Urano T, Kubota Y, Shinoda H, Koto T, Shinoda K, Inoue M, Shiomi T, Ikeda E, Tsubota K, Suda T, Oike Y, Ishida S Selective suppression of pathologic, but not physiologic, retinal neovascularization by blocking the angiotensin II type 1 receptor. Invest. Ophthalmol. Vis. Sci., 2005-03-01;46(3):1078-84. 2005-03-01 [PMID: 15728568] (Mouse)		Mouse
Maynard SE, Min JY, Merchan J, Lim KH, Mondal S, Stillman IE, Epstein FH, Karumanchi SA Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J. Clin. Invest., 2003-03-01;111(5):649-58. 2003-03-01 [PMID: 12618519] (Rat)		Rat
Show All 14 Publications. Collapse Publications.

Array MVR200B

• VEGFR2/KDR/Flk-1 Antibodies
• VEGFR2/KDR/Flk-1 Antibody Pair
• VEGFR2/KDR/Flk-1 ELISA Kits
• VEGFR2/KDR/Flk-1 Proteins
• VEGFR2/KDR/Flk-1 ELISAs
• VEGFR2/KDR/Flk-1 Proteins and Enzymes