Mouse VEGF-D DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Vascular endothelial growth factor D (VEGF-D) is a homodimeric ligand of VEGF R3/Flt-4 and is synthesized with N- and C-terminal propeptides. Fully processed VEGF-D containing only the VEGF homology domain can additionally bind and activate VEGF R2/KDR/Flk-1. VEGF-D is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. VEGF R3 is strongly expressed in lymphatic endothelial cells and is essential for regulation of the growth and differentiation of lymphatic endothelium. While VEGF-C is the critical ligand for VEGF R3 during embryonic lymphatic development, while VEGF-D is most active in neonatal lymphatic maturation and bone growth.

We have publications tested in 1 confirmed species: Mouse.

Showing Publications 1 - 5 of 5.

Publications using DY469	Applications	Species
Allam, RM;El Kerdawy, AM;Gouda, AE;Ahmed, KA;Abdel-Mohsen, HT; Benzimidazole-oxindole hybrids as multi-kinase inhibitors targeting melanoma Bioorganic chemistry 2024-02-26 [PMID: 38457953] (Mouse)		Mouse
LR Lemmerman, MHH Balch, JT Moore, D Alzate-Cor, MA Rincon-Ben, A Salazar-Pu, S Gnyawali, HN Harris, W Lawrence, L Ortega-Pin, L Wilch, IB Risser, AJ Maxwell, S Duarte-San, D Dodd, GP Guio-Vega, DM McTigue, WD Arnold, SM Nimjee, CK Sen, S Khanna, C Rink, N Higuita-Ca, D Gallego-Pe Nanotransfection-based vasculogenic cell reprogramming drives functional recovery in a mouse model of ischemic stroke Science Advances, 2021-03-19;7(12):. 2021-03-19 [PMID: 33741587] (Mouse)		Mouse
Débora C Bastos Effects of fatty acid synthase inhibitors on lymphatic vessels: an in vitro and in vivo study in a melanoma model Lab. Invest, 2016-12-05;0(0):. 2016-12-05 [PMID: 27918556] (Mouse)		Mouse
Tan K, Chong S, Wong F, Evrard M, Tan S, Keeble J, Kemeny D, Ng L, Abastado J, Angeli V Neutrophils contribute to inflammatory lymphangiogenesis by increasing VEGF-A bioavailability and secreting VEGF-D. Blood, 2013-10-10;122(22):3666-77. 2013-10-10 [PMID: 24113869] (Mouse)		Mouse
Kivela R, Silvennoinen M, Lehti M, Kainulainen H, Vihko V Effects of acute exercise, exercise training, and diabetes on the expression of lymphangiogenic growth factors and lymphatic vessels in skeletal muscle. Am. J. Physiol. Heart Circ. Physiol., 2007-08-31;293(4):H2573-9. 2007-08-31 [PMID: 17766486] (Mouse)		Mouse

Array DY469

• VEGF-D Antibodies
• VEGF-D ELISA Kits
• VEGF-D Lysate
• VEGF-D Protein
• VEGF-D ELISAs
• VEGF-D Proteins and Enzymes