Mouse uPAR DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The urokinase-type Plasminogen Activator Receptor (uPAR) is a GPI-anchored protein that binds to both the inactive and active forms of uPA. This interaction serves to localize and enhance the proteolytic activity of uPA, leading to increased conversion of Plasminogen to Plasmin. uPA also triggers uPAR-mediated signal transduction, activation of protein tyrosine kinases, gene expression, cell adhesion, and chemotaxis. uPAR can additionally regulate cell adhesion by direct binding to Vitronectin and preventing Integrins from binding to their ligands.

We have publications tested in 1 confirmed species: Mouse.

Showing Publications 1 - 4 of 4.

Publications using DY531	Applications	Species
C Amor, J Feucht, J Leibold, YJ Ho, C Zhu, D Alonso-Cur, J Mansilla-S, JA Boyer, X Li, T Giavridis, A Kulick, S Houlihan, E Peerschke, SL Friedman, V Ponomarev, A Piersigill, M Sadelain, SW Lowe Senolytic CAR T cells reverse senescence-associated pathologies Nature, 2020-06-17;0(0):. 2020-06-17 [PMID: 32555459] (Mouse)		Mouse
Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease Nat. Med, 2016-12-12;0(0):. 2016-12-12 [PMID: 27941791] (Mouse)		Mouse
Soluble Urokinase Receptors in Focal Segmental Glomerulosclerosis: A Review on the Scientific Point of View J Immunol Res, 2016-07-18;2016(0):2068691. 2016-07-18 [PMID: 27504461] (Mouse)		Mouse
Spinale J, Mariani L, Kapoor S, Zhang J, Weyant R, Song P, Wong H, Troost J, Gadegbeku C, Gipson D, Kretzler M, Nihalani D, Holzman L A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease. Kidney Int, 2014-10-29;87(3):564-74. 2014-10-29 [PMID: 25354239] (Mouse)		Mouse

Array DY531

• uPAR Antibodies
• uPAR Antibody Pair
• uPAR Lysate
• uPAR Proteins
• uPAR Proteins and Enzymes
• uPAR ELISAs