Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Mouse sVEGFR2/Flk-1 DuoSet ELISA, 15 Plate
CD309 antigen
CD309
EC 2.7.10
EC 2.7.10.1
Fetal liver kinase 1
fetal liver kinase-1
Flk1
Flk-1
FLK1tyrosine kinase growth factor receptor
KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
Kinase insert domain receptor
KRD1
Ly73
Protein-tyrosine kinase receptor flk-1
soluble VEGFR2
vascular endothelial growth factor receptor 2
VEGF R2
VEGFR
VEGFR2
VEGFR-2
Background
VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.