Mouse ST2/IL-33R Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

ST2, also known as IL-1 R4, is a component of the receptor for the proinflammatory cytokine Interleukin-33. The IL-33 receptor additionally includes IL-1 RAcp which also associates with IL-1 RI and IL-1 R rp2/IL-1 R6. A soluble form of ST2 functions as a decoy receptor. IL-33 promotes Th2-biased immune responses, resulting in eosinophilia, mast cell activation, and allergic inflammation. In addition, IL-33 enhances inflammation-associated hypernociception and protects from atherosclerosis and cardiac myocyte hypertrophy. Soluble ST2 is elevated in the serum under inflammatory conditions including allergic asthma, sepsis, trauma, dengue fever, pulmonary disease, and lupus. It is also associated aortic stenosis, congestive cardiomyopathy, and risk of cardiovascular heart failure and death.

We have publications tested in 1 confirmed species: Mouse.

Showing Publications 1 - 9 of 9.

Publications using MST200	Applications	Species
L Xu, C Wei, Y Chen, Y Wu, X Shou, W Chen, D Lu, H Sun, W Li, B Yu, X Wang, X Zhang, Y Yu, Z Lei, R Tang, J Zhu, Y Li, L Lu, H Zhou, S Zhou, C Su, X Chen IL-33 induces thymic involution-associated naive T cell aging and impairs host control of severe infection Nature Communications, 2022-11-12;13(1):6881. 2022-11-12 [PMID: 36371464] (Mouse)		Mouse
K Takenaga, M Akimoto, N Koshikawa, H Nagase Cancer cell-derived interleukin-33 decoy receptor sST2 enhances orthotopic tumor growth in a murine pancreatic cancer model PLoS ONE, 2020-04-27;15(4):e0232230. 2020-04-27 [PMID: 32340025] (Mouse)		Mouse
J Yang, A Ramadan, DK Reichenbac, M Loschi, J Zhang, B Griesenaue, H Liu, KL Hippen, BR Blazar, S Paczesny Rorc restrains the potency of ST2+ regulatory T cells in ameliorating intestinal graft-versus-host disease JCI Insight, 2019-03-07;0(0):. 2019-03-07 [PMID: 30694220] (Mouse)		Mouse
AM Ramadan, E Daguindau, JC Rech, K Chinnaswam, J Zhang, GL Hura, B Griesenaue, Z Bolten, A Robida, M Larsen, JA Stuckey, CY Yang, S Paczesny From proteomics to discovery of first-in-class ST2 inhibitors active in vivo JCI Insight, 2018-07-26;3(14):. 2018-07-26 [PMID: 30046004] (Mouse)		Mouse
C Hampton, R Rosa, D Szeto, G Forrest, B Campbell, R Kennan, S Wang, CH Huang, L Gichuru, X Ping, X Shen, K Small, J Madwed, JJ Lynch Effects of carvedilol on structural and functional outcomes and plasma biomarkers in the mouse transverse aortic constriction heart failure model SAGE Open Med, 2017-03-30;5(0):2050312117700. 2017-03-30 [PMID: 28491305] (Mouse)		Mouse
Soluble IL-33 receptor sST2 inhibits colorectal cancer malignant growth by modifying the tumour microenvironment Nat Commun, 2016-11-24;7(0):13589. 2016-11-24 [PMID: 27882929] (Mouse)		Mouse
Tancevski I, Nairz M, Duwensee K, Auer K, Schroll A, Heim C, Feistritzer C, Hoefer J, Gerner R, Moschen A, Heller I, Pallweber P, Li X, Theurl M, Demetz E, Wolf A, Wolf D, Eller P, Ritsch A, Weiss G Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2. EMBO Mol Med, 2014-04-06;6(6):810-20. 2014-04-06 [PMID: 24755316] (Mouse)		Mouse
Jiang X, McClellan SA, Barrett RP, Zhang Y, Hazlett LD Vasoactive intestinal peptide downregulates proinflammatory TLRs while upregulating anti-inflammatory TLRs in the infected cornea. J. Immunol., 2012-06-01;189(1):269-78. 2012-06-01 [PMID: 22661083] (Mouse)		Mouse
Hontelez S, Ansems M, Karthaus N Dendritic cell-specific transcript: dendritic cell marker and regulator of TLR-induced cytokine production. J. Immunol., 2012-05-21;189(1):138-45. 2012-05-21 [PMID: 22615205] (Mouse)		Mouse

Array MST200

• ST2/IL-33R Antibodies
• ST2/IL-33R Antibody Pair
• ST2/IL-33R ELISA Kit
• ST2/IL-33R Proteins
• ST2/IL-33R ELISAs
• ST2/IL-33R Proteins and Enzymes