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Mouse/Rat RGM-C/Hemojuvelin Quantikine ELISA Kit

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Summary
Reactivity Mu, RtSpecies Glossary
Applications ELISA
Conjugate
HRP

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Mouse/Rat RGM-C/Hemojuvelin Quantikine ELISA Kit Summary

Background
The Quantikine Mouse/Rat RGM-C/Hemojuvelin Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse and rat RGM-C in cell culture supernates, tissue homogenates, serum, and plasma. It contains NS0-expressed recombinant mouse RGM-C and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant factor accurately. Resul...ts obtained using natural RGM-C showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural RGM-C.
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Specificity
Recombinant and natural mouse and rat RGM-C/Hemojuvelin
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Hfe2

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Interference observed with 1 or more available related molecules.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse/Rat RGM-C/Hemojuvelin Quantikine ELISA Kit

  • DL-M
  • haemojuvelin
  • hemochromatosis type 2 (juvenile)
  • Hemojuvelin
  • HFE2
  • HFE2AMGC23953
  • HJV
  • HJVHemochromatosis type 2 protein
  • JH
  • repulsive guidance molecule c
  • RGMC
  • RGM-C
  • RGMCRGM domain family member C

Background

The repulsive guidance molecule (RGM) family of molecules contains three uniquely structured GPI-linked glycoproteins that participate in a variety of activities. Termed RGM-A, -B and -C, they are 40-45 kDa in size, show generally nonoverlapping fetal expression patterns, and serve as BMP-4 receptors. RGM-A and -C are plasma membrane bound, while RGM-B is generally microsomal in location. RGM-A and -B are associated with neurons, while RGM-C regulates skeletal muscle and hepatocyte function.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

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Bioinformatics

Gene Symbol Hfe2