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Mitofilin Antibody (S03-6H5)

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Western Blot: Mitofilin Antibody (S03-6H5) [NBP3-15060] - Western blot detection of Mitofilin in K562, Molt-4, Raji cell lysates using Mitofilin Rabbit mAb (1:500 diluted). Predicted band size: 84kDa. Observed band ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
S03-6H5
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Mitofilin Antibody (S03-6H5) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide of human Mitofilin (Uniprot#: Q16891)
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
IMMT
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1/1000-1/5000
Theoretical MW
84 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
Preservative
0.01% Sodium Azide
Purity
Affinity purified

Alternate Names for Mitofilin Antibody (S03-6H5)

  • DKFZp779P1653
  • inner membrane protein, mitochondrial
  • MGC111146
  • Mic 60
  • Mic60
  • MICOS Complex Subunit MIC60
  • mitochondrial (mitofilin)
  • mitofilin
  • motor protein
  • p87/89
  • proliferation-inducing gene 4

Background

Mitochondria are the center of cellular energy production and essential metabolic reactions. As double membrane-bound organelles, mitochondria from different species, tissues, and metabolic states are highly polymorphic in nature, yet exhibit common structural features. The ultrastructural variations in mitochondrial architecture occur mainly due to the differences in the amount and shape of cristae. Abundant cristae are found in mitochondria from tissues where energy demand is high. Analysis of the human heart mitochondrial proteome shows that mitofilin is one of the most abundant mitochondrial proteins. It appears to play an important role in the maintenance of cristae morphology. Mitofilin was originally described as heart muscle protein (HMP) because of its high expression in the heart.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Research Areas for Mitofilin Antibody (NBP3-15060)

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Blogs on Mitofilin.

Mitofilin and the Mitochondrial Inner Membrane Organizing System (MINOS)
Mitofilin was originally described as a heart muscle protein due to its high expression in the heart. Recently, analysis of the human heart mitochondrial proteome demonstrated that Mitofilin is one of the most abundant mitochondrial proteins (1). Rese...  Read full blog post.

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Bioinformatics

Gene Symbol IMMT