Immunocytochemistry/ Immunofluorescence: Mind Bomb 1/MIB1 Antibody [NBP1-85210] - Staining of human cell line U-2 OS shows localization to nuclear membrane, plasma membrane & vesicles. Antibody staining is shown in ...read more
Immunohistochemistry-Paraffin: Mind Bomb 1/MIB1 Antibody [NBP1-85210] - Staining of human hippocampus shows moderate cytoplasmic positivity in neuronal cells.
This antibody was developed against Recombinant Protein corresponding to amino acids: LDLEIVQSLQHGHGGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANIVRSGDAAQGAEGGTSQFQVGDLVQVCYDLERIKLLQRGHGEWAEAM
Predicted Species
Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MIB1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Mouse reactivity reported in scientific literature (PMID: 30590051).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for Mind Bomb 1/MIB1 Antibody
DAPK-interacting protein 1
DIP1
DIP-1FLJ90676
DKFZp686I0769
DKFZp761M1710
E3 ubiquitin-protein ligase MIB1
EC 6.3.2
EC 6.3.2.-
KIAA1323
MGC129660
MIB
MIB1
Mind Bomb 1
Mind bomb homolog 1
mindbomb homolog 1 (Drosophila)
ubiquitin ligase mind bomb
ubiquitin ligase protein MIB1
Zinc finger ZZ type with ankyrin repeat domain protein 2
ZZANK2
ZZANK2MGC129659
ZZZ6
Background
E3 ubiquitin ligase protein mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. It positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. It probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Reviews for Mind Bomb 1/MIB1 Antibody (NBP1-85210) (0)
There are no reviews for Mind Bomb 1/MIB1 Antibody (NBP1-85210).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
=
÷
Review this Product
Be the first to review our Mind Bomb 1/MIB1 Antibody and receive a gift card or discount.