Human MGMT ELISA Kit (Colorimetric)

O6-Methylguanine-DNA Methyltransferase (MGMT) is an important DNA repair protein involved in tumor cell resistance to the cytotoxic activity of chemotherapeutic alkylating agents. This protein is also effective in protecting normal cells against the genotoxic and carcinogenic effects of DNA alkylation. The alkylating drug resistance is caused by MGMT's ability to remove DNA alkyl groups introduced in the O6 position of guanine. MGMT is expressed in highly variable amounts, depending upon the cell and tissue type, species, and cellular growth characteristics. In addition, MGMT activity varies among groups of tumors and within a particular type of tumor.

MGMT antibodes are useful tools for DNA repair studies and for some cancer research.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Verified Customer			10/14/2022	View Summary Sample Tested Cancer cell lysates Lot 20101025 Comments Comments The Human MGMT ELISA was used to assess MGMT expression in Temozolomide-Resistant versus parental glioma lines. Results were very consistent.
	5 reviewed by: MARINA KOUTSIOUMPA			04/18/2022	View Summary Sample Tested Human Glioma cells, whole cell lysates Lot 20101025

Array NBP2-60580

• MGMT Antibodies
• MGMT ELISA Kit
• MGMT Lysate
• MGMT Proteins