MDR3/ABCB4 Antibody (P3II-26) Summary
Immunogen |
Selected after immunization with a fusion protein of Gluthathione S Transferase and a fragment of MDR3/ABCB4 (amino acids 629-692) |
Specificity |
Reacts with internal epitope of MDR3/ABCB4. Does not cross-react with the human MDR1 P-gp. |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
ABCB4 |
Purity |
Protein G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence 1:20-1:50
- Immunohistochemistry
- Immunohistochemistry-Frozen 1:2
- Western Blot
|
Packaging, Storage & Formulations
Storage |
Store at 4C. |
Buffer |
PBS, 0.1% BSA |
Preservative |
0.02% Sodium Azide |
Purity |
Protein G purified |
Alternate Names for MDR3/ABCB4 Antibody (P3II-26)
Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. (provided by RefSeq)
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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