Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Description
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. (provided by RefSeq)
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
5244 |
| Alternate Names |
- ABC21
- ATP-binding cassette sub-family B member 4
- ATP-binding cassette, sub-family B (MDR/TAP), member 4
- EC 3.6.3
- EC 3.6.3.44
- MDR2
- MDR3MDR2/3
- multidrug resistance protein 3
- multiple drug resistance 3
- P glycoprotein 3/multiple drug resistance 3
- PFIC-3
- P-glycoprotein 3
- P-glycoprotein-3/multiple drug resistance-3
- PGY3GBD1
|
