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MBTPS1 Antibody - BSA Free

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Western Blot: MBTPS1 Antibody [NBP3-05160] - Paraffin-embedded human colon using MBTPS1 antibody at dilution of 1:100 (40x lens).
Western Blot: MBTPS1 Antibody [NBP3-05160] - Paraffin-embedded human colon using MBTPS1 antibody at dilution of 1:100 (40x lens).
Immunocytochemistry/ Immunofluorescence: MBTPS1 Antibody [NBP3-05160] - Analysis of U2OS cells using MBTPS1 antibody . Blue: DAPI for nuclear staining.
Immunohistochemistry-Paraffin: MBTPS1 Antibody [NBP3-05160] - Paraffin-embedded human stomach using MBTPS1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry-Paraffin: MBTPS1 Antibody [NBP3-05160] - Paraffin-embedded human colon cancer using MBTPS1 antibody at dilution of 1:100 (40x lens).

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP3-05160
    • Availability
      Product Discontinued

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MBTPS1 Antibody - BSA Free Summary

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 803-1052 of human MBTPS1 (NP_003782.1). ITQTFKDQGLEVLKQETAVVENVPILGLYQIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGSVTPERMEGNHLHRYSKVLEAHLGDPKPRPLPACPRLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVVLAFFVVQINKAKSRPKRRKPRVKRPQLMQQVHPPKTPSV
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MBTPS1
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin
Theoretical MW
117 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS with 50% glycerol, pH7.3.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for MBTPS1 Antibody - BSA Free

  • EC 3.4.21.112
  • Endopeptidase S1P
  • KIAA0091
  • KIAA0091MGC138712
  • MBTPS1
  • membrane-bound transcription factor peptidase, site 1
  • membrane-bound transcription factor protease, site 1
  • PCSK8
  • S1P
  • S1PMGC138711
  • SEDKF
  • site-1 protease
  • SKI1
  • SKI-1
  • SKI-1membrane-bound transcription factor site-1 protease
  • subtilisin/kexin isozyme-1
  • Subtilisin/kexin-isozyme 1

Background

The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MBTPS1